Consensus and controversy in the management of paediatric and adult patients with ovarian immature teratoma: the Malignant Germ Cell International Consortium perspective.
eClinicalMedicine. March 2024
F. Pashankar, M.J. Murray, J. Gell, N. MacDonald, J. Shamash, D.F. Billmire, L. Klosterkemper, T. Olson, M.S. Hirsch, M. Lockley, S. Stoneham, A.L. Frazier
Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence
Nature Communications. May 6 2023
L. Xu, J.L. Pierce, A. Sanchez, K.S. Chen, A. A. Shukla, N.J. Fustino, S.H. Stuart, A, Bagrodia, X. Xiao, L. Guo, M. Krailo, F. Shaikh, D.F. Billmire, F. Pashankar, J. Bestrashniy, J.W. Oosterhuis, Ad J. M. Gillis, Y. Xie, L. Teot, J. Mora, J.N. Poynter, Dinesh Rakheja, Leendert H. J. Looijenga, Bruce W. Draper, A.L. Frazier, J.F. Amatruda
Expanding homogeneous culture of human primordial germ cell-like cells maintaining germline features without serum or feeder layers
PubMed Central. Feb 10, 2022
M. Kobayashi, M. Kobayashi, J. Odajima, K. Shioda, Y. Sun Hwang, K. Sasaki, P. Chatterjee, C. Kramme, R. Kohman, G.. Church, Amanda R. Loehr, R.S. Weiss, H. Jüppner, J. Gell, C. Lau, and T. Shioda
Clinicopathologic predictors of outcome in children with stage 1 testicular germ cell tumors: A pooled post hoc analysis of trials from the Children’s Oncology Group.
Journal of Pediatric Urology. May 7, 2022
N. Singla, J. Wong, S. Singla, M. Krailo, L. Huang, F. Shaikh, D. Billmire, F. Rescorla, J. Ross, B. Dicken, J.F. Amatruda, A.L. Frazier
Addressing the diagnostic and therapeutic dilemmas of ovarian immature teratoma: Report from a clinicopathologic consensus conference
European Journal of Cancer. September 1, 2022
F. Pashankar, K. Hanley, M. Lockley, S. Stoneham, M.R. Nucci, M. Reyes -Múgica, E. Elishaev, R. Vang, J. Veneris, H. Rytting, T. Olson, K. Hazard, A. Covens, R. Arora, D. Billmire, A. Al-Ibraheemi, T. M. Ulbright, A.L. Frazier and M.S. Hirsch
Advancing clinical and translational research in germ cell tumours (GCT): recommendations from the Malignant Germ Cell International Consortium
British Journal of Cancer. October 13, 2o22
A. Fonseca, J. Lobo, Florette K. Hazard, Joanna Gell, P. Nicholls, R.S Weiss, L.Klosterkemper, S.L. Volchenboum, J.C. Nicholson, A. L. Frazier, J.F. Amatruda, A. Bagrodia, M. Lockley & M. J. Murray
Cisplatin Resistance.
Cancer Letters. October 2021.
Skowron MA, Oing C, Bremmer F, Ströbel P, Bokemeyer C, Murray MJ, Coleman N, Amatruda JF, Honecker F, Albers P, Nettersheim D.
A multi-institutional pooled analysis demonstrates that circulating miR-371a-3p alone is sufficient for testicular malignant germ cell tumor diagnosis
Clinical Genitourinary Cancer. September 2021
J. Piao, J.T. Lafin, C.G. Scarpini, M.M. Nuño, I. Syring, K. Dieckmann, G. Belge, J. Ellinger, J.F. Amatruda, A. Bagrodia, N. Coleman, M.D. Krailo, A.L. Frazier, M.J. Murray
Circulating miRNAs, the Next-Generation Serum Biomarkers in Testicular Germ Cell Tumours: A Systematic Review
European Urology. June 2021
Leão R, Albersen M, Looijenga LHJ, Tandstad T, Kollmansberger C, Murray MJ, Culine S, Coleman N, Belge G, Hamilton RJ, Dieckmann K-P.
Imaging Appearance of Nongerminoma Pediatric Ovarian Germ Cell Tumors Does Not Discriminate Benign from Malignant Histology
Journal of Pediatric and Adolescent Gynecology. June 2021
D. Billmire, B. Dicken, F. Rescorla, J. Ross, J. Piao, L. Huang, M. Krailo, F. Pashankar, A.L. Frazier, Children’s Oncology Group.
The Road Ahead For Circulating miRNAs in Diagnosis and Management of Testicular Germ Cell Tumors
Molecular Diagnosis & Therapy. April 2021
J.T. Lafin, M.J. Murray, N. Coleman, A.L. Frazier, J.F. Amatruda, A. Bagrodia.
Management of Germ Cell Tumors in Pediatric Patients
Surgical Oncology Clinics of North America. April 2021
B.R. Weil, D.F. Billmire.
Neonatal Malignant Disorders Germ Cell Tumors
Clinics in Perinatology. March 2021
R. Shah, B.R. Weil, C.B. Weldon, J.F. Amatruda, A.L. Frazier.
Outcomes of Adolescent Males with Extracranial Metastatic Germ Cell Tumors: A Report From the Malignant Germ Cell Tumor International Consortium
Cancer. January 2021
Shaikh F., Stark D., Fonseca A., Dang H., Xia C., Krailo M., Pashankar P., Rodriguez-Galindo C., Olson T., Nicholson J.C., Murray M.J., Amatruda J.F., Billmire D., Stoneham S., and Frazier A.L.
Development of a Data Model and Data Commons for Germ Cell Tumors
JCO Clinical Cancer Informatics. 2020 June
Ci B, Yang D, Krailo M, Xia C, Yao B, Luo D, Zhou Q, Xiao G, Skapek SX, Murray MJ, Amatruda JF, Klosterkemper L, Shaikh F, Faure-Conter C, Fresneau B, Volchenboum S, Stoneham S, Nicholson JC, Lopes LF, Frazier AL, Xie YN
Contemporary Management of Ovarian Germ Cell Tumors and Remaining Controversies
Gynecologic Oncology. 2020 June
Veneris J, Mahajan P, Frazier AL
Clinical Utility of Circulating miR-371 a-3p for the management of patients with Intracranial Malignant Germ Cell Tumors.
Neuro-Oncology Advances. 2020 April
Murray MJ, Ajithkumar TV, Harris F, Williams RM, Jalloh I, Cross J, Ronghe M, Ward DM, Scarpini CG, Nicholson JC and Colemen N on behalf of the CCLG
A Serum MicroRNA-371a-3p Levels Predict Viable Germ Cell Tumor in Chemotherapy-naïve Patients Undergoing Retroperitoneal Lymph Node Dissection.
European Urology. 2020 February
J. Lafin, N. Singla, S. Woldu, Y. Lotan, C. Lewis, K. Majmudar, A. Savelyeva, P. Kapur, V. Margulis, D. Strand, M. Murray, J. Amatruda, A. Bagrodia.
Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence.
European Urology Supplements. 2019 September
Xu L, Pierce JL, Sanchez A, Chen KS, Shukla AA, Fustino NJ, Stuart SH, Bagrodia A, Krailo MD, Shaikh F, Billmire D, Pashankar F, Bestrashniy J, Oosterhuis JW, Biermann K, Gillis AJM, Stoop JH, Xie Y, Teot L, Mora JH, Poynter JN, Rakheja D, Looijenga LHJ, Draper BW, Frazier AL, Amatruda JF.
Abstracts of the International Extracranial Germ Cell Tumour Conference.
2019 September
Germ Cell Tumors in Adolescents and Young Adults.
Journal of Oncology Practice. 2019 August
A. Fonseca, A.L. Frazier, F. Shaikh.
Results from the UK Children’s Cancer and Leukaemia Group study of extracranial germ cell tumours in children and adolescents (GCIII).
European Journal of Cancer. 2019 July
S. Depani, S. Stoneham, M. Krailo, C. Xia, J. Nicholson.
α-Fetoprotein as a Predictor of Outcome for Children With Germ Cell Tumors: A Report From the Malignant Germ Cell International Consortium.
Cancer. 2019 July
A.F. O’Neill, C. Xia, M. Krailo, F. Shaikh, F. Pashankar, D. Billmire, T. Olson, J. Amatruda, D. Villaluna, L. Huang, M. Malogolowkin, C. Rodriguez-Galindo, A.L. Frazier.
Can circulating microRNAs solve clinical dilemmas in testicular germ cell malignancy?
Nature Reviews Urology. 2019 July
M.J. Murray, N. Coleman.
Recurrent ovarian immature teratoma in a 12-year-old girl: Implications for management.
Gynecologic Oncology. 2019 June
Frazer JL, Hook CE, Addley HC, Jackson CR, Latimer JA, Nicholson JC, Murray MJ
MicroRNA Dysregulation in Malignant Germ Cell Tumors: More Than a Biomarker?
Journal of Clinical Oncology. 2019 June
M. Murray, N. Coleman.
Identification of testicular cancer driver genes by a cross-species comparative oncology approach.
Andrology. 2019 May
Sanchez A, Xu L, Pierce JL, Lafin JT, Abe D, Bagrodia A, Frazier AL, Amatruda JF.
AYA testis cancer: The unmet challenge.
Pediatric Blood and Cancer. 2019 May
S. Stoneham, M. Murray, B. Thomas, M. Williamson, C. Sweeney, A. Fraizer
New insights into germ cell tumor genomics.
Andrology. 2019 March
J.T. Lafin, A. Bagrodia, S. Woldu, J.F. Amatruda
Cost Analysis of Noninvasive Blood-Based MicroRNA Testing Versus CT Scans for Follow-up in Patients With Testicular Germ-Cell Tumors.
Clinical Genitourinary Cancer. 2019 March
Charytonowicz D, Aubrey H, Bell C, Ferret M, Tsui K, Atfield R, Coleman N, Murray MJ, Wilson ECF
Detection of Relapse by Tumor Markers Versus Imaging in Children and Adolescents With Nongerminomatous Malignant Germ Cell Tumors: A Report From the Children’s Oncology Group.
Journal of Clinical Oncology. 2018 Nov
A. Fonseca, C. Xia, A.J. Lorenzo, M. Krailo, T.A. Olson, F. Pashankar, M.H. Malogolowkin, J.F. Amatruda, D.F. Billmire, C. Rodriguez-Galindo, A.L. Frazier, and F. Shaikh
Comparison of Carboplatin vs. Cisplatin in the Treatment of Pediatric Extracranial Malignant Germ Cell Tumors: A Report of the Malignant Germ Cell International Consortium.
European Journal of Cancer. 2018 May
A.L. Frazier, S. Stoneham, C. Rodriguez-Galindo, H. Dang, C. Xia, T.A. Olson, M.J. Murray, J.F. Amatruda, F. Shaikh, F. Pashankar, D. Billmire, M. Krailo, D. Stark, M. Brougham, J.C. Nicholson, and J.P. Hale
Is Carboplatin-based Chemotherapy as Effective as Cisplatin-based Chemotherapy in the Treatment of Advanced-stage Dysgerminoma in Children, Adolescents and Young Adults?
Gynecologic Oncology. 2018 May
R. Shah, C. Xia, M. Krailo, J.F. Amatruda, S.G. Arul, D.F. Billmire, W.E. Brady, A. Covens, D.M. Gershenson, Juliet P. Hale, J. Hurteau, M. J.Murray, J.C. Nicholson, T.A. Olson, F.Pashankar, C. Rodriguez-Galindo, F. Shaikh, D. Stark, A.L. Frazier, and S. Stoneham
EGF Receptor and mTORC1 are Novel Therapeutic Targets in Nonseminomatous Germ Cell Tumors.
Molecular Cancer Therapeutics. 2018 Apr
K.S. Chen, N. Fustino, A.A. Shukla, E.K. Stroup, A. Budhipramono, C. Ateek, S.H. Stuart, K. Yamaguchi, P. Kapur, A.L. Frazier, L. Lum, L.H.J. Looijenga, T.W. Laetsch, D. Rakheja, and J.F. Amatruda
Pediatric Germ Cell Tumors: A Developmental Perspective.
Advances in Urology. 2018 Feb
J.L. Pierce, A.L. Frazier, and J.F. Amatruda
Future-Proofing Blood Processing for Measurement of Circulating miRNAs in Samples from Biobanks and Prospective Clinical Trials.
Cancer, Epidemiology, Biomarkers & Prevention. 2018 Feb
M.J. Murray, H.L. Watson, D. Ward, S. Bailey, M. Ferraresso, J.C. Nicholson, V.J. Gnanapragasam, B. Thomas, C.G. Scarpini, and N. Coleman
Ovarian Yolk Sac Tumors: Does Age Matter?
International Journal of Gynecologic Oncology. 2018 Jan
C. Faure Conter, D. Gershenson, J. Hurteau, A. Covens, F. Pashankar, M. Krailo, D. Billmire, C. Patte, B. Fresneau, F. Shaikh, S. Stoneham, J. Nicholson, M. Murray, and A.L. Frazier
Testicular Cancer in 2017: Sequencing Advances Understanding.
Nature Reviews: Urology. 2017 Dec
M.J. Murray and C. Turnbull
Gonadal Dysgenesis is Associated with Worse Outcome in Patients with Ovarian Nondysgerminomatous Tumors: A Report of the Children’s Oncology Group AGCT 0132 Study.
Pediatric Blood & Cancer. 2017 Nov
B.J. Dicken, D.F. Billmire, Mark Krailo, C. Xia, F. Shaikh, J.W. Cullen, T.A. Olson, F. Pashankar, M.H. Malogolowkin, J.F. Amatruda, F.J. Rescorla, R. Egler, J. Ross, C. Rodriguez-Galindo, A.L. Frazier
Variants in BAK1, SPRY4, and GAB2 are Associated with Pediatric Germ Cell Tumors: a Report from the Children’s Oncology Group.
Genes, Chromosomes & Cancer. 2017 Jul
E. Marcotte, N. Pankratz, J.F Amatruda, A.L. Frazier, M. Krailo, S. Davies, J. Starr, C.C Lau, M. Roesler, E. Langer, C. Hallstrom, A.J. Hooten, and J.N Poynter
A Robust Protocol to Quantify Circulating Cancer Biomarker MicroRNAs.
Methods in Molecular Biology, Chapter 18, vol. 1580. 2017
E. Bell, H.L. Watson, S. Bailey, M.J. Murray, and N. Coleman
Reduced and Compressed Cisplatin-Based Chemotherapy in Children and Adolescents With Intermediate-Risk Extracranial Malignant Germ Cell Tumors: A Report From the Children’s Oncology Group.
Journal of Clinical Oncology. 2017 Apr
F. Shaikh, John W. Cullen, Thomas A. Olson, F. Pashankar, M.H. Malogolowkin, D. Villaluna, M. Krailo, J.F. Amatruda, D.F. Billmire, F.J. Rescorla, R.A. Egler, J.H. Ross, B.J. Dicken, M. Schlatter, C, Rodriguez-Galindo, and A.L. Frazier
Germ Cell Tumors of the Ovary.
Textbook of Uncommon Cancer (pp 518-532). 2017 Mar
D.E. Matei, A.L. Frazier, J.A. Hurteau, and F.D. Pashankar
Conundrums in the Management of Malignant Ovarian Germ Cell Tumors: Toward Lessening Acute Morbidity and Late Effects of Treatment.
Gynecology Oncology. 2016 Nov
D.M. Gershenson and A.L. Frazier
Patient-Reported Measures of Hearing Loss and Tinnitus in Pediatric Cancer and Hematopoietic Stem Cell Transplantation: A Systematic Review.
Journal of Speech, Language and Hearing Research. 2016 Oct
D. Stark, A.R. Rosenberg, D.L. Johnston, K.R. Knight, L. Caperon, El.M. Uleryk, A.L. Frazier, and L. Sung
Risk of second gonadal cancers in women and children with germ cell tumors.
Cancer. 2016 Jul
Z.W. Liao, M.C. Rodrigues, J.N. Poynter, J.F. Amatruda, C. Rodriguez-Galindo, and A.L. Frazier
Paediatric Extracranial Germ-Cell Tumors.
Lancet Oncology. 2016 Apr
F. Shaikh, M.J. Murray, J F. Amatruda, N.Coleman, J.C. Nicholson, J.P. Hale, F. Pashankar, Sara J. Stoneham, Jennifer N. Poynter, T.A. Olson, D.F. Billmire, D.l Stark, C. Rodriguez-Galindo, and A.L.Frazier
Is Adjuvant Chemotherapy Indicated in Ovarian Immature Teratomas? A Combined Data Analysis From the Malignant Germ Cell Tumor International Collaborative.
Cancer. 2016 Jan 15
F. Pashankar, J.P. Hale, H. Dang, M. Krailo, W.E. Brady, C. Rodriguez-Galindo, J.C. Nicholson, M.J. Murray, D.F. Bilmire, S. Stoneham, G.S. Arul, T.A. Olson, D. Stark, F. Shaikh, J.F. Amatruda, A. Covens, D.M. Gershenson, and A.L. Frazier
Germ Cell Tumors: Treatment Consensus Across All Age Groups through MaGIC (Malignant International Germ Cell Consortium).
Cancer. 2016 Jan 15
J.A. Hurteau and M. Febbraro
Revised Risk Classification for Pediatric Extracranial Germ Cell Tumors Based on 25 Years of Clinical Trial Data from the United Kingdom and United States.
Journal of Clinical Oncology. 2015 Jan 10
A.L. Frazier, J.P. Hale, C. Rodriguez-Galindo, H. Dang, T. Olson, M.J Murray, J.F. Amatruda, C. Thornton, G. Suren Arul, D. Billmire, F. Shaikh, F. Pashankar, S. Stoneham, M. Krailo, and J.C. Nicholson
Pediatric and Adolescent Extracranial Germ Cell Tumor: The Road to Collaboration.
Journal of Clinical Oncology. 2015 Sep 20
T.A. Olson, M.J. Murray, C. Rodriguez-Galindo, J.C. Nicholson, D. F. Billmire, M. Krailo, H. M. Dang, J.F. Amatruda, Claire M. Thornton, G. Suren Arul, S.J. Stoneham, F. Pashankar, D. Stark, F. Shaikh, D.M. Gershenson, A. Covens, J. Hurteau, S.P. Stenning, D.R. Feldman, P.S. Grimison, R.A. Huddart, C. Sweeney, T. Powles, L. Fernando Lopes, S. dos Santos Agular, G. Chinnaswamy, S. Khaleel, S. Abouelnaga, J.P. Hale, and A.L. Frazier
Adolescents and Young Adults With a “Rare” Cancer: Getting Past Semantics to Optimal Care for Patients With Germ Cell Tumors.
Oncologist. 2014 Jul
S.Stoneham, J.P. Hale, C. Rodriguez-Galindo, H. Dang, T. Olson, M. Murray, J.F. Amatruda, C. Thornton, G.S. Arul, D. BiIlmire, M. Krailo, D. Stark, A. Covens, J. Hurteau, S. Stenning, J.C. Nicholson, D. Gershenson, and A.L. Frazier
Is there a Role for Carboplatin in the Treatment of Malignant Germ Cell Tumors? A systematic Review of Adult and Pediatric Trials.
Pediatric Blood & Cancer. 2013 Apr
F. Shaikh, P. Nathan, J. Hale, E. Uleryk, and A.L. Frazier